Hogeschool van Amsterdam

Urban Vitality

Protein delivery in the intensive care unit

optimal or suboptimal?

Article

Emerging evidence suggests that exogenous protein/amino acid supplementation has the potential to improve the recovery of critically ill patients. After a careful review of the published evidence, experts have concluded that critically ill patients should receive up to 2.0-2.5 g/kg/d of protein. Despite this, however, recent review of current International Nutrition Survey data suggests that protein in critically ill patients is underprescribed and grossly underdelivered. Furthermore, the survey suggests that most of protein administration comes from enteral nutrition (EN) despite the availability of products and protocols that enhance the delivery of protein/amino acids in the intensive care unit (ICU) setting. While future research clarifies the dose, timing, and composition for exogenous protein administration, as well as identification of patients who will benefit the most, ongoing process improvement initiatives should target a concerted effort to increase protein intake in the critically ill. This assertion follows from the notion that current patients are possibly being harmed while we wait for confirmatory evidence. Further research should also develop better tools to enable bedside practitioners to monitor optimal or adequate protein intake for individual patients. Finally, exploring the effect of combining adequate protein delivery with early mobility and/or resistance exercise in the ICU setting has the greatest potential for improving the functional outcomes of survivors of critical illness and warrants further study.

Reference Heyland, D. K., Weijs, P. J. M., Coss-Bu, J. A., Taylor, B., Kristof, A. S., O'Keefe, G. E., & Martindale, R. G. (2017). Protein delivery in the intensive care unit: optimal or suboptimal? Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 32(1_suppl), 58S-71S. https://doi.org/10.1177/0884533617691245
Published by  Faculty Sports and Nutrition 1 April 2017

Publication date

Apr 2017

Author(s)

Daren K. Heyland
Jorge A. Coss-Bu
Beth Taylor
Arnold S. Kristof
Grant E. O'Keefe
Robert G. Martindale